Current Drug
Shortages and Alternatives

Acetylcysteine 10% vials Alternatives: Acetylcysteine 20% vials

Pipercillin/Tazobactam 2.25gm, 3.375gm, 4.5gm – multiple NDCs – Limited supply Pipercillin/Tazobactam 2.25gm, 3.375gm, 4.5gm – multiple NDCs – Limited supply

Bicillin LA 1.2mu & 2.4mu Injection (Pen G) – NDC: 60793-702-10, 60793-701-10 – Limited Availability Alternatives: Antimicrobials based on sensitivity Ampicillin INJ for IV Penicillin INJ of IV

MVI -12 and MVI- Adult Injection vial – Hospira Alternatives: Infuvite

Cefepime for Injection 1gm, 2gm vial -multiple NDCs – Limited Availability Alternatives: Ceftriaxone 500mg, 1gm Cefazolin 500mg, 1gm

Dextrose 50% Injection (25gm/50ml) –limited availability Dextrose 50% Injection (25gm/50ml) –limited availability

Dextrose 70% Injection 500ml and 2000ml bags – limited availabiltiy Dextrose 70% Injection 500ml and 2000ml bags – limited availabiltiy

Epinephrine 0.1mg/mL Alternatives: Epipen 0.15mg and 0.3mg

Protonix IV powder for injection 40mg Vial – limited availability Alternatives: Other IV PPI – Nexium (esomeprazole) or Prevacid (lansoprazole) Oral protonix (pantoprazole) Other oral proton pump inibitors – Omeprazole, Lansoprazole, Esomeprazole

Bactroban 2% nasal ointment (1gram tubes) – NDC 00029-1526-11 Alternatives: Mupirocin 2% ointment -22gm tube

Sodium Bicarbonate Injection 8.4% – limited availability Sodium Bicarbonate Injection 8.4% - limited availability

Methotrexate Injection – Multiple NDCs Alternatives: The choice of alternative agent must be patient –specific and based on neoplasm type and location. No single agent can be substituted for methotrexate. Use oral Methotrexate if possible.

Theophylline ER Tablet 100mg, 200mg, 300mg Alternatives Theophylline oral solution (elixophyllin 80mg/15ml) Theo-24 ER capsules – 100mg 200mg, 300mg

Isosorbide Dinitrate ER 40mg (Isordil) – NDC: 57664-600-88 Alternatives: Isosorbide Dinitrate 5mg, 10mg 20mg, 30mg tablets

Acetylcysteine 10% vials Alternatives:
Acetylcysteine 20% vials

Disopyramide Phosphate (Norpace) – multiple Strengths Alternatives:
Amiodarone
Calcium channel blockers- verapamil
Beta blockers – metoprolol, atenolol

Pipercillin/Tazobactam 2.25gm, 3.375gm, 4.5gm – multiple NDCs – Limited supply Pipercillin/Tazobactam 2.25gm, 3.375gm, 4.5gm – multiple NDCs – Limited supply

Bicillin LA 1.2mu & 2.4mu Injection (Pen G) – NDC: 60793-702-10, 60793-701-10 – Limited Availability Alternatives:
Antimicrobials based on sensitivity
Ampicillin INJ for IV
Penicillin INJ of IV

MVI -12 and MVI- Adult Injection vial – Hospira Alternatives:
Infuvite

Cefepime for Injection 1gm, 2gm vial -multiple NDCs – Limited Availability Alternatives:
Ceftriaxone 500mg, 1gm
Cefazolin 500mg, 1gm

Dextrose 50% injection (25gm/50ml) Dextrose 50% injection (25gm/50ml)

Epinephrine 0.1mg/mL Alternatives
Epipen 0.15mg and 0.3mg

Factive (Gemifloxacin) 320mg Alternatives:
Other flouroquinolones depending on microorganism such as Levaquin
Azithromycin

Sodium Bicarbonate Injection 8.4% – limited availability Sodium Bicarbonate Injection 8.4% - limited availability

Acetylcysteine 10% vials Alternatives: Acetylcysteine 20% vials.

Pipercillin/Tazobactam 2.25gm, 3.375gm, 4.5gm – multiple NDCs – Limited supply Sodium Chloride 0.9% inj bags – 100ml Disopyramide Phosphate (Norpace) – multiple Strengths Alternatives: Amiodarone Calcium channel blockers- verapamil Beta blockers – metoprolol, atenolol

Bicillin LA 1.2mu & 2.4mu Injection (Pen G) – NDC: 60793-702-10, 60793-701-10 – Limited Availability Alternatives: Antimicrobials based on sensitivity Ampicillin INJ for IV Penicillin INJ of IV

MVI -12 and MVI- Adult Injection vial – Hospira Alternatives: Infuvite

Cefepime for Injection 1gm, 2gm vial -multiple NDCs – Limited Availability Alternatives: Ceftriaxone 500mg, 1gm Cefazolin 500mg, 1gm

Risperidone ODT tablets all strengths – Mylan – Discontinuation Alternatives: Zyprexa Zydis (olanzapine ODT – 5mg, 10mg)
Ability ODT (aripiprazole ODT – 10mg, 15mg)

Montelukast oral granules 4mg NDC 00378-6040-93 Mylan – Discontinuation Alternatives: Montelukast 4mg tablet chewable, 5mg tablet chewable, 10mg tablet

Calcium Gluconate Injection Vial 10% – multiple NDCs Alternatives : calcium carbonate 500mg tablets

Cefepime for Injection 1gm, 2gm vial -multiple NDCs – Limited Availability Alternatives: Ceftriaxone 500mg, 1gm
Cefazolin 500mg, 1gm

Promethazine for Injection Vial 25mg – NDC 00641-0928-25 Westward
50mg- NDC 00641-0929-25 Westward
Alternatives: Reglan (metoclopramide 10mg )
Zofran (ondansetron 4mg, 8mg)